TABLE 3.

Correlation between the SQM MICs and treatment response compared with the M27-A MICs and treatment response

Isolate	MIC		Day 3				Day 6
	SQM	M27-A method	% Survivala		Fungal burdenb		% Survival		Fungal burden
			1 mg/kg/day [0.9, 0.5]c	5 mg/kg/day [1.0, 0.3]	1 mg/kg/day [0.6, 0.8]	5 mg/kg/day [1.0, 0.2]	1 mg/kg/day [0.9, 0.5]	5 mg/kg/day [1.0, 0.3]	1 mg/kg/day [1.0, 0.3]	5 mg/kg/day [1.0, 0.2]
1	1.0	0.125	90	90	13	19	90	90	1.9	9.3
2	54	>64	33	55	106	123	33	55	85	86
3	1.0	>64 (trd)	90	95	51	0.02	90	95	0.15	0.06
4	1.0	>64 (tr)	65	90	93	11	65	90	0.67	0.13

^aNumber of animals alive at the indicated day/total number of animals infected × 100. 

^b10⁴ CFU/g of kidney tissue. 

^cPearson's coefficients of correlation between the SQM and M27-A MICs (in that order) and therapeutic outcome are given in brackets. 

^dtr, trailing growth.