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. 2022 Mar 29;9:821404. doi: 10.3389/fnut.2022.821404

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Copyright © 2022 Wang, Huang, Ding, Zhou, Gao, Han, Zhou, Ke, Rao, Chen and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of BS, BSNPs, and SASP treatment on histopathological alteration and inflammatory cytokines in the colonic mucosa of DSS-induced colitis. (A) Representative images of colonic segments. (B) Histological scores. (C) TNF-α expression. (D) Interleukin 6 (IL-6) expression. (E) Interleukin 1 β (IL-1β) expression. Values are expressed as the mean ± SEM (n = 6). Means without a common letter are significantly different at p < 0.05 using one-way ANOVA followed by Tukey’s test for post hoc analysis.