TABLE 4.

Results of kyoto encyclopedia of genes and genomes (KEGG) analysis on hub targets of candidate Chinese herbal medicine (CCHM) in the treatment of methamphetamine (METH) addiction.

Pathway	Counts	Genes
Dopaminergic synapse	5	DRD3, DRD2, SLC6A3, MAOA, MAOB
Cocaine addiction	4	DRD2, SLC6A3, MAOA, MAOB
Neuroactive ligand-receptor interaction	5	DRD3, DRD2, ADRA2A, ADRA1B, ADRA2C
Alcoholism	4	DRD2, SLC6A3, MAOA, MAOB
Amphetamine addiction	3	SLC6A3, MAOA, MAOB
Serotonergic synapse	3	MAOA, MAOB, HTR3A
cGMP-PKG signaling pathway	3	ADRA2A, ADRA1B, ADRA2C