Table 2. Number of death events across groups and association of body fat, LVH and all-cause death with different adjustment model.
| Outcome, models | Outcome number and event rates by subgroups, HR (95%CI), P value | ||||
| Lower body fat, no LVH
(n = 956) |
Lower body fat, LVH
(n = 727) |
Higher body fat, no LVH
(n = 242) |
Higher body fat, LVH
(n = 318) |
P for interaction | |
| This table shows the unadjusted and multivariate analysis of relationship between body fat percentage, LVH, and all-cause death. After adjusting for age, sex, cardiovascular risk factors, heart failure related parameters, cardiovascular metabolic indicators, angiographic lesions, number of stent implanted, cardiovascular secondary preventive drug treatment and other confounding
factors, patients with a high body fat percentage had different prognoses stratified by LVH existence status. Compared with patients with a lower body fat percentage and no LVH, patients with a higher body fat rate and LVH had the highest risk of all-cause death (HR = 3.49; 95% CI: 1.40−8.69; P = 0.007), while patients with a higher body fat percentage but no LVH had no statistically significant difference in risk of death compared with the control group (HR = 2.03, 95% CI: 0.70−5.92; P= 0.195). There was statistically significant interaction between body fat percentage and LVH (P for interaction = 0.003). ACE: angiotensin converting enzyme; ARBs: angiotensin II receptor blockers; LVEF: left ventricular ejection fraction；LVH: left ventricular hypertrophy. | |||||
| All-cause death | 24 (2.5%) | 57 (7.8%) | 13 (5.4%) | 26 (8.2%) | |
| Unadjusted hazard ratio | Reference | 3.19 (1.98−5.15), P < 0.001 | 2.10 (1.07−4.13), P = 0.031 | 3.16 (1.81−5.50), P < 0.001 | 0.003 |
| Adjusted for age and sex | Reference | 3.04 (1.88−4.93), P < 0.001 | 1.57 (0.80−3.10), P = 0.191 | 2.44 (1.39−4.27), P = 0.002 | |
| Adjustd for age, sex, LVEF and serum creatinine | Reference | 2.08 (1.26−3.43), P = 0.004 | 1.56 (0.79−3.08), P = 0.198 | 1.86 (1.05−3.30), P = 0.033 | |
| Adjusted for age, sex, LVEF, serum creatinine, hypertension, diabetes, current smoker, systolic blood pressure, diastolic blood pressure, heart rate, triglyceride, glucose, hemoglobin, ACE inhibitors/ARBs, beta-blockers, left main of three-vessel disease, stent numbers | Reference | 2.45 (1.06−5.62), P = 0.035 | 2.03 (0.70−5.92), P = 0.195 | 3.49 (1.40−8.69), P = 0.007 | |