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. 2022 Mar 29;13:864956. doi: 10.3389/fimmu.2022.864956

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Copyright © 2022 Li, Zhang, Li, Su, Duan, Zhang, An, Ni, Li and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of sEVs. (A) NTA displayed that the diameters of most sEVs in each group were around 100nm. (B) TEM showed that sEVs in each group were 50–200 nm disc-like vesicles with bilayer membrane. (C) Western blot analysis showed that sEVs of all groups express CD9, CD63, and TSG101.