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. 2022 Mar 29;13:864956. doi: 10.3389/fimmu.2022.864956

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Copyright © 2022 Li, Zhang, Li, Su, Duan, Zhang, An, Ni, Li and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of T cell subsets from eye and lymph node in EAU. (A) Representive figures of intracellular staining of IFN-γ⁺IL-17⁺, Foxp3⁺ in eyes and lymph nodes derived CD4⁺T cells from PBS, Rapa, sEV, and Rapa-sEV treated mice with EAU. (B) The percentage of CD4⁺IFN-γ⁺IL-17⁺ cells in eyes. (C) The percentage of CD4⁺IFN-γ⁺IL-17A⁺ cells in cervical draining lymph nodes. (D) The percentage of CD4⁺Foxp3⁺ cells in eyes. (E) The percentage of CD4⁺Foxp3⁺ cells in cervical draining lymph nodes. Values are expressed as the mean ± SD of three mice per group. *P < 0.05, one-way ANOVA.