Table 1.
Monoclonal antibody infusion process logistics and timing metrics from the 3 National Disaster Medical System-supported infusion sites and related strengths and challenges to inform implementation
Logistics and timing metrics | Site 1 | Site 2 | Site 3 | Implementation considerations | |
---|---|---|---|---|---|
Strengths | Challenges | ||||
Infusion site type | Walk-up tent infusion site | Appointment-based outpatient infusion site | Appointment-based tent infusion site | Walk-up sites were beneficial in communities with low health care. system engagement Appointment-based sites facilitated batch preparation of monoclonal antibody infusion doses, shortening the overall time of the appointment. 30-minute staggering between patient group arrivals improved patient flow due to 15- to 30-minute intake process. |
Walk-up sites exhibited longer wait times for on-demand pharmacy preparation of the monoclonal antibody. Batch preparation of monoclonal antibodies resulted in unused doses for walk-up systems. Walk-up site had large variability in timing due to confirming the patient’s SARS-CoV-2 positivity upon arrival. Appointment-based sites required increased staffing and planning to schedule patients. |
Process type | Emergency medical visit | Outpatient infusion procedure | Outpatient infusion procedure | ||
Infusion site start date | Dec 30, 2020 | Jan 7, 2021 | Jan 8, 2021 | ||
Total patients infused during study period
(Start-Feb 26 2021) |
397 | 824 | 402 | ||
Average rate (patients/day) | 7 | 16 | 8 | ||
Most significant logistics barriers | Confirming SARS-CoV-2 patient positivity criteria | Coordination with pharmacy for monoclonal antibody preparation | Coordination with pharmacy for monoclonal antibody preparation | ||
Coordination with pharmacy for monoclonal antibody preparation | Staffing needs for scheduling process | Staffing needs for scheduling process | |||
Hours of operation | 24 hours/day | Monday-Friday | Monday-Friday | ||
7 days a week | 9:00 am-5:00 pm | 9:00 am-5:00 pm |