Table 5. Intra-day and inter-day precision and accuracy for clopidogrel, 2-Oxo-CLP, and CAMD.
| Analyte | Nominal concentration (ng/mL) | Intra-day (n=6) | Inter-day (n=3) | |||||
| Mean assayed value (ng/mL) | Accuracy
(RE [%]) |
Precision
(RSD [%]) |
Mean assayed value (ng/mL) | Accuracy
(RE [%]) |
Precision
(RSD [%]) |
|||
| 2-Oxo-CLP: 2-oxo-clopidogrel; CAMD: clopidogrel active metabolite derivative; RE: relative error, RE=(nominal sample concentration–tested sample concentration)/nominal sample concentration×100%; RSD: relative standard deviation, RSD=SD value/mean value×100%. | ||||||||
| Clopidogrel | 0.1 | 0.1 | 15.2 | 4.8 | 0.1 | 12.2 | 18.7 | |
| 20 | 20.7 | 3.6 | 2.2 | 20.4 | 2.0 | 3.7 | ||
| 40 | 41.8 | 4.5 | 2.7 | 42.4 | 5.9 | 5.6 | ||
| 2-Oxo-CLP | 1 | 1.1 | 5.8 | 4.7 | 1.0 | 2.8 | 19.2 | |
| 20 | 21.2 | 5.8 | 4.0 | 20.6 | 2.9 | 6.4 | ||
| 40 | 41.0 | 2.7 | 5.8 | 42.4 | 6.0 | 7.7 | ||
| CAMD | 1 | 1.0 | 2.8 | 8.5 | 1.0 | 4.0 | 14.8 | |
| 40 | 42.0 | 5.0 | 4.3 | 42.0 | 5.1 | 8.8 | ||
| 80 | 83.0 | 3.7 | 7.2 | 84.6 | 5.8 | 5.9 | ||