Table 4.

Management and outcomes of Cryptococcus spp. infection of the central nervous system.

	Sarcoidosis (n = 5)	Non-sarcoidosis (n = 11)	p-value
Time from diagnosis to treatment initiation (days)	0.20 ± 0.45	0.45 ± 0.93	0.76
Initial 2-week liposomal B amphotericin and flucytosine bitherapy*	4	8	1.00
Fluconazole maintenance therapy**	4	10	1.00
Treatment total duration (days)	34 ±29	66 ±13	0.04
Death due to Cryptococcosis	1	1	1.00
Long-term sequelae	1/4 Cerebellar ataxia	2/10 Motor function	1.00 -

^*Intravenous liposomal B amphotericin: 3 mg/kg per day. Intravenous flucytosine: 25 mg/kg every 6 h.

^**Fluconazole per os: 400 mg per day for 2 weeks, then 200 mg per day. Bold values are statistically significant.