Skip to main content
. 2022 Mar 29;16:798995. doi: 10.3389/fnint.2022.798995

FIGURE 1.

FIGURE 1

Relationship between obesity-related inflammation and senescence. NF-κB is the central regulator in the stress response and may be activated by various stimuli. Among them, pro-inflammatory cytokines secreted by adipose tissue during obesity. This factor has also been related to the aging process by contributing to cellular senescence through the senescence-associated secretory phenotype (SASP).