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. 2022 Mar 29;13:868347. doi: 10.3389/fmicb.2022.868347

TABLE 2.

Comparative results for povidone iodine at three times of exposure according to Mentor® implants.

Treatment Median (IQR) log ufc/ml p * Median (IQR) % live cells p * Median (IQR) % bacterial density p *
28 μm Siltex™ vs. 36 μm CPG™ PI 1′ 28 μm Siltex™ 0.00 (0.00–0.00) 1 100.00 (94.50–100.00) 0.262 0.25 (0.18–0.33) 0.087
PI 1′ 36 μm CPG™ 0.00 (0.00–0.00) 96.45 (90.65–100.00) 0.19 (0.14–0.23)
PI 3′ 28 μm Siltex™ 0.00 (0.00–0.00) 1 95.90 (88.35–98.00) 0.596 0.31 (0.14–0.50) 0.001
PI 3′ 36 μm CPG™ 0.00 (0.00–0.00) 95.95 (86.78–100.00) 0.14 (0.0–0.18)
PI 5′ 28 μm Siltex™ 0.00 (0.00–0.00) 1 99.00 (78.38–100.00) 0.934 0.17 (0.06–0.21) 0.253
PI 5′ 36 μm CPG™ 0.00 (0.00–0.00) 97.00 (93.20–100.00) 0.14 (0.07–0.17)
28 μm Siltex™ vs. 10 μm smooth PI 1′ 28 μm Siltex™ 0.00 (0.00–0.00) 0.004 100.00 (94.50–100.00) 0.041 0.25 (0.18–0.33) <0.001
PI 1′ 10 μm smooth 0.00 (0.00–1.35) 100.00 (100.00–100.00) 0.09 (0.06–0.12)
PI 3′ 28 μm Siltex™ 0.00 (0.00–0.00) 0.037 95.90 (88.35–98.00) 0.002 0.30 (0.14–0.50) <0.001
PI 3′ 10 μm smooth 0.00 (0.00–0.33) 100.00 (96.40–100.00) 0.07 (0.02–0.11)
PI 5′ 28 μm Siltex™ 0.00 (0.00–0.00) <0.001 99.00 (78.38–100.00) 0.120 0.17 (0.06–0.21) 0.032
PI 5′ 10 μm smooth 1.00 (0.00–1.50) 100.00 (94.78–100.00) 0.07 (0.03–0.12)
10 μm smooth vs. 36 μm CPG™ PI 1′ 10 μm smooth 0.00 (0.00–1.35) 0.004 100.00 (100.00–100.00) 0.004 0.09 (0.06–0.12) 0.001
PI 1′ 36 μm CPG™ 0.00 (0.00–0.00) 96.45 (90.65–100.00) 0.19 (0.14–0.23)
PI 3′ 10 μm smooth 0.00 (0.00–0.33) 0.037 100.00 (96.40–100.00) 0.036 0.07 (0.02–0.11) 0.002
PI 3′ 36 μm CPG™ 0.00 (0.00–0.00) 95.95 (86.78–100.00) 0.14 (0.08–0.18)
PI 5′ 10 μm smooth 1.00 (0.00–1.50) <0.001 100.00 (94.78–100.00) 0.072 0.07 (0.03–0.12) 0.087
PI 5′ 36 μm CPG™ 0.00 (0.00–0.00) 97.00 (93.20–100.00) 0.14 (0.07–0.17)

PI, povidone iodine; IQR, interquartile range; cfu, colony forming units; bacterial density, bacteria/μm2.

*Values in bold represent statistical significance.