TABLE 3.
Results for povidone iodine at three times of exposure in Polytech® implants.
| Prosthesis | Treatment | Median (IQR) log ufc/ml | p * | Median (IQR) % live cells | p * | Median (IQR) % bacterial density | p * |
| <10 μm Polysmooth™ | SS 1′ | 2.67 (2.33–3.16) | <0.001 | 100.00 (100.00–100.00) | 0.599 | 0.20 (0.12–0.35) | 0.153 |
| PI 1′ | 0.00 (0.00–2.23) | 100.00 (100.00–100.00) | 0.12 (0.07–0.29) | ||||
| SS 3′ | 2.78 (2.53–3.15) | <0.001 | 100.00 (100.00–100.00) | 0.752 | 0.22 (0.08–0.39) | 0.392 | |
| PI 3′ | 0.00 (0.00–1.72) | 100.00 (100.00–100.00) | 0.12 (0.04–0.20) | ||||
| SS 5′ | 2.82 (1.94–3.13) | <0.001 | 100.00 (98.73–100.00) | 0.270 | 0.18 (0.11–0.20) | 0.392 | |
| PI 5′ | 0.00 (0.00–1.51) | 100.00 (89.90–100.00) | 0.19 (0.12–0.30) | ||||
| 25 μm MESMO® | SS 1′ | 3.70 (3.61–3.96) | <0.001 | 100.00 (100.00–100.00) | 0.339 | 0.17 (0.14–0.19) | 0.022 |
| PI 1′ | 0.00 (0.00–0.00) | 100.00 (100.00–100.00) | 0.11 (0.10–0.13) | ||||
| SS 3′ | 3.57 (2.98–3.78) | <0.001 | 100.00 (100.00–100.00) | 0.317 | 0.11 (0.06–0.15) | 0.668 | |
| PI 3′ | 0.00 (0.00–0.00) | 100.00 (100.00–100.00) | 0.10 (0.05–0.27) | ||||
| SS 5′ | 3.80 (3.38–4.04) | <0.001 | 100.00 (100.00–100.00) | 0.509 | 0.10 (0.07–0.18) | 0.087 | |
| PI 5′ | 0.00 (0.00–0.00) | 100.00 (100.00–100.00) | 0.21 (0.07–0.68) | ||||
| 25–50 μm Polytxt® | SS 1′ | 4.32 (4.16–5.04) | <0.001 | 100.00 (100.00–100.00) | 0.037 | 0.03 (0.02–0.07) | 0.001 |
| PI 1′ | 0.00 (0.00–0.00) | 100.00 (98.08–100.00) | 0.01 (0.00–0.03) | ||||
| SS 3′ | 4.60 (4.25–5.22) | <0.001 | 100.00 (100.00–100.00) | 0.903 | 0.06 (0.04–0.13) | < 0.001 | |
| PI 3′ | 0.00 (0.00–0.00) | 100.00 (100.00–100.00) | 0.01 (0.01–0.02) | ||||
| SS 5′ | 4.61 (4.51–5.20) | <0.001 | 100.00 (99.18–100.00) | 0.146 | 0.04 (0.02–0.07) | 0.002 | |
| PI 5′ | 0.00 (0.00–0.00) | 100.00 (90.83–100.00) | 0.01 (0.01–0.02) | ||||
| 50–100 μm macrotextured | SS 1′ | 3.84 (3.31–4.21) | <0.001 | 100.00 (100.00–100.00) | 0.50 | 0.05 (0.03–0.07) | 0.775 |
| PI 1′ | 0.00 (0.00–0.00) | 100.00 (93.65–100.00) | 0.05 (0.04–0.07) | ||||
| SS 3′ | 3.82 (3.18–4.06) | <0.001 | 100.00 (99.38–100.00) | 0.071 | 0.05 (0.03–0.10) | 0.775 | |
| PI 3′ | 0.00 (0.00–0.00) | 99.45 (94.18–100.00) | 0.05 (0.04–0.07) | ||||
| SS 5′ | 3.70 (3.52–4.10) | <0.001 | 100.00 (95.78–100.00) | 0.686 | 0.03 (0.02–0.08) | 0.775 | |
| PI 5′ | 0.00 (0.00–0.00) | 100.00 (94.63–100.00) | 0.05 (0.04–0.07) |
SS, sterile saline; PI, povidone iodine; IQR, interquartile range; cfu, colony forming units; bacterial density, bacteria/μm2.
*Values in bold represent statistical significance in favor of PI.