Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 29;16:851012. doi: 10.3389/fnins.2022.851012

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Wauters, Ceulemans, Schol, Farré, Tack and Vanuytsel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Luminal and cellular elements of the duodenal barrier. (A) The intestinal lumen is separated from the epithelium by a mucus layer formed by mucin glycoproteins, mainly MUC2 from goblet cells, in which bacterial residence is limited by the secretion of antimicrobial peptides (from Paneth or epithelial cells) and sIgA (from plasma cells). (B) Tight junctions, adherens junctions and desmosomes are important cell-to-cell adhesion proteins that regulate the epithelial barrier function, and initiate and stabilize enterocyte adhesion in the gut. AMP, antimicrobial peptides; MUC2, Mucin 2; sIgA, secretory immunoglobulin A; ZO, zonula occludens. This figure was created with elements from Smartservier.