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. 2022 Mar 29;16:851012. doi: 10.3389/fnins.2022.851012

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Copyright © 2022 Wauters, Ceulemans, Schol, Farré, Tack and Vanuytsel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Functional assessment of permeability (ex vivo). (A) Experimental set-up of Ussing chambers. (B) Equivalent electrical circuit model with the transcellular (R_trans or sum of apical (R_api) and basolateral (R_bas) resistances) and the paracellular (R_para) resistances in a simple epithelium (TEER is the sum of all individual resistances). Fd4, fluorescein isothiocyanate-labeled 4 kDa dextran; TEER, transepithelial electrical resistance.