Table 2.
Inhibitory activity of identified compounds on enzymes involved in glucose-producing pathways.
| Compound | G6Pase IC50 (μg/mL) | FBPase IC50 (μg/mL) |
|---|---|---|
| Caffeic acid (4) | 719.8 ± 192.9 | - |
| kaempferol-3-O-(2,6-di-O-trans-ρ-coumaryl)-β-d-glucopyranoside (5) | 27.7 ± 1.9 | 52.5 ± 6.4 |
| Chlorogenic acid * | 179.7 ± 27.5 | - |
| Adenosine 5′-monophosphate + | - | 16.9 ± 2.2 |
IC50 values expressed as mean ± SEM of two assays in duplicate. G6Pase: glucose-6-phosphatase. FBPase: fructose-1,6-bisphosphatase. * G6Pase positive control. + FBPase positive control.