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. 2022 Mar 25;14(7):1370. doi: 10.3390/nu14071370

Table 9.

Effects of α-Bisabolol in preclinical models of gastrointestinal diseases.

Dose/Route/Duration Model Major Mechanisms Reference
100 mg/kg p.o. Ethanol (96%, 1 mL per animal) induced gastric damage in rats ↓ gastric damage [114]
100 or 200 mg/kg p.o. Ethanol (0.2 mL/animal p.o.) and Indomethacin (20 mg/kg p.o.) induced ulcer model in mice ↓ gastric lesions
↑ GSH
[115]
100 and 200 mg/kg, p.o. Ethanol (0.2 mL) induced gastric lesion in mice ↓ MDA, MPO, ↑ SOD, ↓ neutrophils influx [116]

Symbols indications: ↑; increase, ↓; decrease.