Table 9.
Dose/Route/Duration | Model | Major Mechanisms | Reference |
---|---|---|---|
100 mg/kg p.o. | Ethanol (96%, 1 mL per animal) induced gastric damage in rats | ↓ gastric damage | [114] |
100 or 200 mg/kg p.o. | Ethanol (0.2 mL/animal p.o.) and Indomethacin (20 mg/kg p.o.) induced ulcer model in mice | ↓ gastric lesions ↑ GSH |
[115] |
100 and 200 mg/kg, p.o. | Ethanol (0.2 mL) induced gastric lesion in mice | ↓ MDA, MPO, ↑ SOD, ↓ neutrophils influx | [116] |
Symbols indications: ↑; increase, ↓; decrease.