Table 10.

Nephroprotective effects of α-Bisabolol.

100 mg/kg p.o. and 500, 250, 125, 62.5 and 31.25 μM	Clamping of the renal artery in the left kidney for 60 min. in rats and Ischemia/reperfusion model on tubular epithelial cells (LLC-MK2) by anaerobic chamber method	↓ creatinine, urea, uric acid ↓ urinary osmolality ↓ FeNa+, FeK+, FeCl− ↓ microalbuminuria ↓ KIM-1, ↓ TBARS, ↑ GSH ↑ cell viability	[118]
1000, 500, 250, 125, 62.5 and 31.25 μM	Ischemia/reperfusion model on human tubular kidney cells (HK2) by anaerobic chamber method	↑ cell viability, ↓ apoptosis, ↓ TBARS, (-) NADPH oxidase ↑ GSH, ↓ NOX4, ↑ ΔΨm, ↓ KIM-1	[119]

Symbols indications: ↑; increase, ↓; decrease, (-); reduce.