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. 2022 Apr 2;14(7):1492. doi: 10.3390/nu14071492

Figure 2.

Figure 2

Oral Microbiome differences between PROP taster groups in response to the CPE rinse. Number of observed ASVs (A), Faith’s phylogenetic diversity (B), and Evenness (C) are alpha diversity metrics while beta diversity is based on Weighted UniFrac distance matrices shown in (D) as a 2D Principal Coordinate analysis (PCoA) plot and in (E) as violin plots. Each point in the PCoA plot represents the mean (±SEM) principal coordinate (PC) score of all individual subjects pre- and post-intervention. In the violin plots, rectangles show the medians and the interquartile ranges (IQRs), the whiskers denote the lowest and highest values that were within 1.5 times the IQR from the first and third quartiles. In NT/ST subjects, Wilcoxon matched-pairs signed-ranks test (two-tailed) was performed to compare pre- and post- intervention samples. Before/After CPE oral rinse, Mann-Whitney test (two-tailed) was performed to compare NT and ST subjects. * p < 0.05 and ** p < 0.01. Pre-intervention: NT n = 10, ST n = 10; Post-intervention: NT n = 10, ST n = 9.