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. 2022 Apr 2;14(7):1483. doi: 10.3390/nu14071483

Table 5.

Statement regarding prevention of vitamin D deficiency in adults.

Consensus Statement Consensus Voting Scale Level of Agreement
In healthy adults without other risk factors, a supplementation of 800–2000 IU/day, for those who want to achieve a targeted/measured 25(OH)D concentration, should be considered during wintertime (mainly November-April) due to insufficient endogenous dermal vitamin D synthesis and depending on the body weight.
Due to decreased skin synthesis in elderly (>65 years), a supplementation of 800–2000 IU/day is recommended throughout the year.
In hospitalized/institutionalized individuals, a supplementation of 800–2000 IU/day is recommended throughout the year.
Women planning a pregnancy should start or maintain the vitamin D supplementation as recommended for healthy adults without other risk factors (800–2000 IU/day). The vitamin D supplementation should be continued throughout pregnancy and lactation.
In certain patients/individuals or conditions 2–3 times higher vitamin D dosages, without using vitamin D doses above the UL of 4000 IU/day, are recommended for prevention compared to healthy adults without other risk factors:
Malabsorption (e.g., cystic fibrosis, inflammatory bowel diseases, bariatric surgery, radiation enteritis)
Obesity (BMI ≥ 30 kg/m2)
Dark skin pigmentation
As vitamin D metabolites are stored in fat and other tissues and gradually released into the blood circulation, a daily or weekly or monthly supplementation regimen is equally effective and safe, if monthly doses are not exceedingly high, for the prevention of vitamin D deficiency.
A tailored approach for vitamin D administration, involving the patients’ preferences of the supplementation regimen (daily, weekly, monthly) might enhance the adherence to preventive vitamin D supplementation.
For the prevention of vitamin D deficiency, the supplementation of oral cholecalciferol (vitamin D3) is recommended.
9 (strongly agree) 30%
8 20%
7 (agree) 50%
6 0%
5 (neutral) 0%
4 0%
3 (disagree) 0%
2 0%
1 (strongly disagree) 0%
 
Overall agreement 100%, consensus endorsed