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. 2022 Mar 28;14(7):1407. doi: 10.3390/nu14071407

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Dynamics of free serum zinc and total serum zinc during COVID-19. (A) Free zinc and (B) total zinc concentrations in sera of COVID-19 patients, separated with regard to patients that survived (“Discharge”) or died (“Death”), in comparison to serum of healthy controls (CTR). Scatter plots depict changes in (C) free and (D) total serum zinc concentrations over time during hospital stay. Data are presented as means ± SD, and significant differences are indicated (Kruskal–Wallis test followed by Dunn’s multiple–comparison test (* p < 0.05; ** p < 0.01; *** p < 0.001) (A,B)), and as scatter plots (C,D), including Spearman correlation coefficients (r) and p values. Data presented in (B) are shown for comparison and were published previously [15].