Table 1.
The Hardy–Weinberg equilibrium (HWE) p-values and distribution of genotype frequencies of selected single-nucleotide polymorphisms (SNPs).
| Genes | Chromosomic Location |
SNPs | Alleles | MAF 1, (%) | HWE, p |
|---|---|---|---|---|---|
| DRD1 | 5 (3′UTR Variant) | rs686 * | G > A | 29.3 | 0.66 |
| DRD2 | 11 (Intron Variant) | rs4648317 | G > A | 89.6 | 0.02 |
| DRD2 | 11 (Intron Variant) | rs4274224 | G > A | 54.1 | 0.42 |
| DRD2 | 11 (Intron Variant) | rs4581480 | C > T | 87 | 0.03 |
| DBH | 9 (3′UTR Variant) | rs1611115 * | C > T | 77.7 | 0.76 |
| MAO B | X (Intron Variant) | rs1799836 | T > C | 53.4 | <0.001 |
| MAO A | X (Downstream variant 3′) | rs660925 | T > C | 60.4 | <0.001 |
| COMT | 22 (Missense Variant in exon 4 Val158Met) | rs4680 * | G > A | 86.2 | <0.001 |
DRD1: dopaminergic receptor D1; DRD2: dopaminergic receptor D2; DBH: dopaminergic beta hydroxylase; MAO B: monoamine oxidase B; MAO A: monoamine oxidase A; COMT: catechol O methyl transferase; SNPs: single-nucleotide polymorphisms; HWE: Hardy–Weinberg equilibrium, G: Guanine; A: Adenine; T: Thymine; C: Cytosine. 1 Major/Reference Allelic Frequency. * Functional polymorphism.