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. 2022 Mar 22;22(7):2447. doi: 10.3390/s22072447

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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3D-rendered volume of normal retinal region (A) and CNV lesion with edema (B–D). The red portion of the volume shows the result of STDEV frame averaging with increased microvasculature specificity, while the green portion of the volume shows the result of mean frame averaging. (A) Organized NFL tracks and vascular branching. (B) The bulge of CNV disrupting the NFL and vasculature. The edemas are apparent in the 3D render of the STDEV vasculature (C) and visualized in 3D orthographic views (D).