Table 1:

Characteristics of eligible cases

	Cases (n=325)
Age (months)
Median (range)	13·3 (2·6–53·1)
Clinical syndrome
Meningitis	158 (49%)
Bacteraemic pneumonia	129* (40%)
Pneumonia with effusion	36 (11%)
Bacteraemia†	2 (<1%)
Method of detection
Culture of isolate	307 (94%)
PCR of cerebrospinal fluid or pleural fluid	18 (6%)
Serotype
Vaccine-type‡	151 (46%)
Vaccine-related§	77 (24%)
Non-vaccine¶	97 (30%)
Medical care
Outpatient	17 (5%)
Admitted to hospitalised without intensive care	187 (58%)
Admitted to hospitalised with intensive care	121 (37%)
Deaths (outcome)
Overall	77 (24%)
In cases of meningitis	57 (36%)
In cases of pneumonia	19 (12%)
In cases of bacteraemia	1 (50%)

Data are number (%), unless otherwise indicated. PCV10=ten-valent pneumococcal conjugate vaccine.

^*Includes eight cases with Streptococcus pueumoniae detected in both blood and pleural fluid.

^†Without pneumonia, meningitis, and sepsis.

^‡PCV10 serotypes 1, 4, 5, 6B, 7F, 9V, 14, 18C, 19F, and 23F.

^§Serotypes not included in PCV10, but in the same serogroup as any of the included serotypes.

^¶Serotypes not included in PCV10 and not in the same serogroup as any of the included serotypes.