Fig. 3.

Comparisons of Discovered Downstream Motif to Other CTCF Data. a We compared our TF-MoDISco motifs from the mutants of ZFs 1 and 2 to aggregated reads from CTCF HT-SELEX cycle 4 and to computationally predicted motifs of CTCF’s DBDs from the RCADE2 model, which was trained on in vitro B1H ZF binding data. b We compared motif hits of the core followed by discovered downstream motif in reads from CTCF HT-SELEX data in cycle 0 to cycle 4. c We compared the strength of the core followed by discovered downstream motif in HeLa cell CTCF peaks from [28] to HeLa peaks from CTCF’s alternative isoform from the same study and HeLa CTCF peaks from ENCODE [39]