Fig. 4 –

Solid stress and porosity response to changes in stiffness without vascular leakiness. In (a-c) the average of tumor and host stiffness E_μ was varied and in (d-f) the ratio of tumor to host stiffness E_R was varied. Radial stress (a & d) and hoop stress (b & e) are presented alongside tissue porosity (c & f). The line color distinguishes each level of E_μ and E_R considered (See Legend in Panel a and Panel d). Solid lines indicate 20% free growth (J_R→0 = 1.2), and dashed lines indicate no growth. The background gradient indicates the smooth transition from tumor to host (left to right). The vertical line marks the nominal tumor boundary. Baseline values were E_μ = 4.6 kPa and E_R = 0.7