Table 1 –

Material parameters for tumor and host tissue. Tumor and host values are denoted by “T” and “H”, respectively.

Parameter	Symbol	Value (Baseline; Range)
Elastic modulus	E	T: (3.8;1.9 – 11.4) kPa (Jamin et al. 2015; Stewart et al. 2017) H: (5.4; 2.7 – 16.2) kPa (Cheng et al. 2008; Franze et al. 2013; Jamin et al. 2015)
Vascular leakiness	LpS	T: (4.2; 2.1 – 8.4) × 10−7 m1s1kg−1 (Baxter and Jain 1989; Pishko et al. 2011) H: 0 m1s1kg−1
Specific wetted surface area	Sw	T: (1.4; 0.7 – 2.8) × 106 m−1 H: (1.4; 0.7 – 2.8 × 106 m−1 (Elmghirbi et al. 2018)
Poisson’s ratio	ν	T: 0.35 H: 0.35 (Kaczmarek et al. 1997; Wang and Sarntinoranont 2019)
Tissue hydraulic conductivity	κ	T: Model dependent H: 2.33 × 10−13 m3s1kg−1 (Elmghirbi et al. 2018; Pishko et al. 2011; Wang and Sarntinoranont 2019)
Porosity	ϕ	T: Model dependent H: 0.2 (Sykova and Nicholson 2008)
Effective vascular pressure	pv	T: 6 mmHg H: 6 mmHg (Elmghirbi et al. 2018)
Fluid dynamic viscosity	μf	T: 3.5 × 10−3 kg1m−1s−1 (Chen et al. 1998; Elmghirbi et al. 2018; Yao et al. 2012)
Karman-Cozeny constant	CKC	5 (Happel and Brenner 1983; Truskey et al. 2009)
Tissue transition center	c	(3 – 4.7) × 10–3 m (This study)
Tissue transition gradient	s	0.75 × 10−3 m (This study)