TABLE 1.

Mutational events causing a stop codon in MTZ-resistant strains

Strain	Type of mutation	Effect	MTZ MIC (μg/ml)
350a2	Insertion of A in position 141	Frameshift: TAA stop codon in position 175	32
7a	Substitution of T for C in position 148	TAG stop codon in position 148	48
84a	Substitution of T for C in position 148	TAG stop codon in position 148	48
342c2	Substitution of T for G in position 223	TAA stop codon in position 223	32
136c2	Substitution of T for G in position 523	TAG stop codon in position 523	12