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. 2022 Mar 28;9:845382. doi: 10.3389/fcvm.2022.845382

Table 1.

Timelines.

Case 1
Index date A 66-year-old male with ischemic cardiomyopathy
and recurrent VTs requiring therapy from ICD
1,5,11 months Repeated ineffective catheter ablations due to
intramural location of the substrate
18 months First SBRT with continuing recurrences of VT
34 months Remapping after the first SBRT
38 months Second SBRT, after 3 months VT disappeared
69 months Last follow-up visit, no arrhythmias
Case 2
Index date A 34-year-old patient with an intramyocardial fibroma
(60 × 40 × 25 mm) in the inferolateral wall of the left
ventricle and recurrent VTs of different morphologies
6 months Empirical circumferential epicardial cryoablation
around the tumor, 6 months without recurrences of
VT
13 months Catheter ablation for recurrences of 2 morphologies
of VT, one non-inducible, other almost incessant
14 months First SBRT, within 6 months all arrhythmias gradually
disappeared
38 months v Re-do catheter ablation, without elimination of VT
due to intramural substrate located in the opposite
side of the tumor
38 months Second SBRT, within 3 months VT disappeared
60 months Last follow-up visit, no arrhythmias
Case 3
Index date A77-year-old male with non-ischemic
cardiomyopathy, aortic valve replacement and
fibrosis in basal region of left ventricle and sporadic
interventions of ICD
70 months Repeated catheter ablation for electrical storm
71 months First SBRT, arrhythmias less frequent
73 months Re-do catheter ablation for VT recurrences in basal
septal region above the previous SBRT, non-inducibility
75 months Second SBRT for incessant VT, leading to slowing
VT to 100 bpm
76 months Re-do catheter ablation in the basal septum,
non-inducibility
77 months Progression of heart failure and cachexia, death