TABLE 1.
Functions of C. autoethanogenum essential genes
| Function | No. of essential genes ona: |
|
|---|---|---|
| Rich medium | Minimal medium + CO | |
| Metabolic pathways | 98 | 156 |
| Ribosome | 38 | 42 |
| Microbial metabolism in diverse environments | 33 | 41 |
| Carbon metabolism | 25 | 30 |
| Aminoacyl-tRNA biosynthesis | 21 | 23 |
| Biosynthesis of amino acids | 18 | 36 |
| Hypothetical | 13 | 24 |
| Peptidoglycan biosynthesis | 11 | 12 |
| Pyruvate metabolism | 9 | 11 |
| Carbon fixation pathways in prokaryotes | 9 | 13 |
| DNA replication | 9 | 11 |
| Amino sugar and nucleotide sugar metabolism | 9 | 9 |
| Oxidative phosphorylation | 7 | 10 |
| Fatty acid metabolism | 6 | 7 |
| Fatty acid biosynthesis | 6 | 7 |
| Propanoate metabolism | 6 | 7 |
| Quorum sensing | 5 | 7 |
| Protein export | 5 | 9 |
| Purine metabolism | 5 | 14 |
| Bacterial secretion system | 5 | 9 |
| RNA degradation | 5 | 7 |
| RNA polymerase | 4 | 4 |
| Pyrimidine metabolism | 4 | 10 |
| Citrate cycle (tricarboxylic acid cycle) | 3 | 7 |
| Phosphotransferase system (PTS) | 2 | 2 |
| Folate biosynthesis | 2 | 5 |
| Biotin metabolism | 1 | 2 |
| Flagellar assembly | 1 | 1 |
| Bacterial chemotaxis | 1 | 2 |
a
Shown are the number of C. autoethanogenum essential genes for various KEGG functional categories on the rich medium YTF and the minimum fermentation medium with CO as a carbon and energy source.