. Author manuscript; available in PMC: 2022 Jul 1.

Published in final edited form as: Brain Behav Immun. 2021 Jan 30;95:45–60. doi: 10.1016/j.bbi.2021.01.026

Table 16.

Multivariable models for associations between GOS-specific TC Scores and 6-month GOS Scores.

Variable OR p-value	Model 1	Model 2	Model 3	Model 4	Model 5
Age	1.0	1.0	1.0	1.0	1.0
	0.916	0.798	0.979	0.938	0.73
Gender	0.72	0.67	0.67	0.75	0.68
Male vs. Female	0.463	0.398	0.378	0.533	0.419
GCS Score	0.76	0.76	0.82	0.78	0.80
*Best in 24 h*	0.0009	0.001	0.016	0.0006	0.007
TC1_GOS: Adaptive IL-7, IL-21	1.22				0.98
TC1_GOS: Adaptive IL-7, IL-21	0.135				0.896
TC2 _GOS : Soluble Molecules sIL-2Ra, sTNFRII		4.73			4.41
TC2 _GOS : Soluble Molecules sIL-2Ra, sTNFRII		0.007			0.013
TC3_GOS: Innate IL-1b, MIP-1b			0.40		0.40
TC3_GOS: Innate IL-1b, MIP-1b			0.116		0.208
TC4 _GOS : Chemokines ITAC, RANTES				1.44	1.29
TC4 _GOS : Chemokines ITAC, RANTES				0.0245	0.204
TC2_GOS × GCS		0.89			0.89
TC2_GOS × GCS		0.046			0.048
TC3_GOS × GCS			1.21		1.18
TC3_GOS × GCS			0.046		0.158

Each model represents a multivariable logistic regression of unfavorable dichotomized GOS score (2,3) adjusting for all covariates. Significant associations (p < 0.05) are bolded and trend level associations are italicized (p < 0.1).