Table 9.
Mass spectrum response intensity results of biomarkers in each group of plasma.
| Metabolites | SHAM | OVX | OVX + QEP |
|---|---|---|---|
| Sphinganine | 138309.00 ± 6744.78 | 97056.17 ± 22274.59** | 141025.50 ± 9526.83## |
| 17a-Hydroxypregnenolone | 24448.17 ± 3624.71 | 335.00 ± 167.34** | 1853.67 ± 1783.68# |
| Arachidonic acid | 306021.17 ± 40505.10 | 162345.17 ± 21232.51** | 267945.17 ± 17032.68## |
| alpha-Linolenic acid | 122533.83 ± 20912.51 | 54490.83 ± 7114.61** | 85953.50 ± 23057.84*,## |
| Corticosterone | 34397.00 ± 12407.63 | 84034.33 ± 9170.16** | 46131.50 ± 2809.61*,## |
| Docosahexaenoic acid | 200855.33 ± 10616.66 | 91945.50 ± 11379.02** | 163005.00 ± 39315.98*,## |
| Phytosphingosine | 205007.17 ± 18840.63 | 137923.33 ± 11720.77** | 214333.50 ± 16804.79## |
| 9E,11E-Octadecadienoic acid | 300927.83 ± 37838.00 | 145755.00 ± 10282.14** | 206023.33 ± 23495.15**,## |
| 11-cis-Retinol | 32096.50 ± 6220.81 | 14648.33 ± 2081.33** | 25166.83 ± 2598.00*,## |
| PC (18:1(11Z)/18:1(11Z)) | 27435.67 ± 3313.67 | 18857.83 ± 5389.77** | 27542.50 ± 1595.79## |
| PC (20:3(5Z,8Z,11Z)/20:3(8Z,11Z,14Z)) | 5557.83 ± 506.47 | 2482.67 ± 319.42** | 5257.00 ± 825.42## |
| LysoPC (20:2(11Z,14Z)/0:0) | 88605.50 ± 11896.04 | 45743.50 ± 6386.17** | 61193.50 ± 6905.02**,## |
| LysoPC (22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0) | 866379.33 ± 135683.28 | 443690.33 ± 67149.98** | 473418.33 ± 53589.55** |
| l-Tryptophan | 305551.00 ± 21872.06 | 219563.67 ± 27319.04** | 270166.83 ± 25780.81*,## |
| Tetrahydrocorticosterone | 67802.50 ± 11770.13 | 6035.83 ± 1400.48** | 10816.67 ± 7143.64** |
| Sphingosine 1-phosphate | 45182.67 ± 7678.10 | 28745.33 ± 11038.43* | 33012.83 ± 5462.94* |
| Cholic acid | 61178.33 ± 36634.00 | 873.00 ± 282.77** | 19495.00 ± 8953.54*,## |
| 1-lyso-2-Arachidonoyl-phosphatidate | 16361.33 ± 3276.19 | 9079.00 ± 1251.38** | 12387.50 ± 6344.67 |
| Glycocholic acid | 20080.83 ± 4372.29 | 607.67 ± 148.67** | 4475.50 ± 644.57**,## |
*p < 0.05 vs. SHAM; **p < 0.01; #p < 0.05 vs. OVX; ##p < 0.01.