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In vitro permeation parameters of IND/Gel, IND-Ts/Gel, and IND-HTs/Gel through excised porcine ear skin (n = 3).
| Formulations | Jss (μg/cm2·h) | Enhancement ratio (ER) |
|---|---|---|
| IND/Gel | 1.11 ± 0.28 | 1.00 |
| IND-Ts/Gel | 1.98 ± 0.60 | 1.78 |
| IND-HTs/Gel | 3.67 ± 0.59**,# | 3.31 |
Data were expressed as mean ± SD (n = 3).
p< .01 compared with the IND/Gel.
p< .05 compared with IND-Ts/Gel.
