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. 2022 Mar 29;12:852515. doi: 10.3389/fonc.2022.852515

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Copyright © 2022 Liu, Xu, Li, Yu, Feng, Xu and Chen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BAP1 acts as a tumor suppressor in kidney renal clear cell carcinoma (KIRC). (A) Pan-cancer analysis of BAP1; (B) Immunohistochemical analysis of BAP1 in renal tumor and normal tissues; (C) Survival analysis comparing high- and low expression of BAP1; (D) Distribution of BAP1 genomic alterations inTCGA KIRC; (E, F) Relationship between copy number alterations and BAP1 expression: scatter plot (E), correlation plot (F). ns, not significant, p ≥ 0.05; *p < 0.05; **p < 0.01; ***p < 0.001.