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. Author manuscript; available in PMC: 2022 Aug 23.
Published in final edited form as: J Am Chem Soc. 2022 Feb 10;144(7):2861–2866. doi: 10.1021/jacs.1c12778

Figure 1.

Figure 1.

(a) Biosynthetic gene cluster and predicted annotations from A. hydrillicola proposed to be responsible for the biosynthesis of AETX. (b) Retrobiosynthetic proposal for AETX (1) biosynthesis from two tryptophan-derived indoles.