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Bridging the gap to improving oocyte competence in IVFD. Follicles from early developmental stages can develop to the antral stage in vitro in the optimized culture systems. Comparing follicles developed in vitro and in vivo will identify critical factors that can improve IVFD to produce mature oocytes competent for embryonic development resulting in live offspring in various species. 2D, two-dimensional; 3D, three-dimensional; IVM, in vitro maturation.
