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. 2022 Apr 12;17(4):e0261165. doi: 10.1371/journal.pone.0261165

Fig 6. Results of gene-based collapsing analysis of CZP responder and non-responder exome sequencing data.

Fig 6

(A) QQ plot of observed vs null FET significance values for CZP super-responders vs non-responders. (B) CZP super-responders are compared to sequence data from 1546 population controls and 55 non-responders, while C shows QQ plot of CZP non-responders compared to 1546 population controls and 19 super-responders. In all three analyses, no individual genes exceeded what was expected under the null hypothesis.