Table 6. Top ten most strongly associated genes in collapsing tests of multiple rare variants.
| Gene | P-value | |
|---|---|---|
| Responders vs. Non-responders + Controls | C11ORF93 | 3.637E-004 |
| CUL2 | 6.964E-004 | |
| PPME1 | 7.715E-004 | |
| EOGT | 8.394E-004 | |
| CROT | 8.583E-004 | |
| PIK3AP1 | 9.998E-004 | |
| OR5AU1 | 9.998E-004 | |
| SAMD10 | 0.0013 | |
| CLRN3 | 0.0016 | |
| KIAA1107 | 0.0016 | |
| Non-responders vs. Responders + Controls | KIAA1522 | 1.01E-004 |
| BTN1A1 | 1.703E-004 | |
| POF1B | 2.297E-004 | |
| IFNA4 | 3.292E-004 | |
| GGN | 3.786E-004 | |
| GREB1 | 3.887E-004 | |
| TSEN54 | 4.814E-004 | |
| EIF3B | 6.756E-004 | |
| ACTL9 | 6.779E-004 | |
| OR11H4 | 0.0011 | |
| Responders vs. Non-responders | CROT | 0.0034 |
| ADAMTS2 | 0.014 | |
| RBMXL3 | 0.014 | |
| ADAMTS16 | 0.0149 | |
| CLRN3 | 0.0149 | |
| CNGB1 | 0.0149 | |
| DUPD1 | 0.0149 | |
| FARSB | 0.0149 | |
| KCNK5 | 0.0149 | |
| KDM3B | 0.0149 |