Table 3.
Fetal characteristics at time of study
| Control (n=12) | IUGR (n=13) | P-value | |
|---|---|---|---|
| Fetal measurements | |||
| Gestational age (d) | 135 ± 1 | 134 ± 1 | 0.16 |
| Fetal weight (g) | 3423 ± 451 | 1961 ± 676 | <0.0001 |
| Hindlimb weight (g) | 344 ± 47† | 185 ± 68 | <0.0001 |
| Hindlimb length (cm) | 36.2 ± 2.2 | 29.0 ± 3.9 | <0.0001 |
| Gastrocnemius weight (g) | 9.2 ± 1.1 | 5.0 ± 1.9 | <0.0001 |
| Biceps femoris weight (g) | 18.9 ± 2.5Δ | 9.9 ± 3.4 | <0.0001 |
| Arterial pH | 7.36 ± 0.01 | 7.34 ± 0.02 | 0.02 |
| PaCO2 (mmHg) | 50.7 ± 1.7 | 51.5 ± 2.7 | 0.39 |
| PaO2 (mmHg) | 20.1 ± 1.8 | 14.6 ± 3.1 | <0.0001 |
| SaO2 (%) | 47.2 ± 4.5 | 26.6 ± 11.6 | <0.0001 |
| Hematocrit (%) | 34.0 ± 3.7 | 34.2 ± 5.0 | 0.92 |
| Arterial blood O2 content (mmol·L−1) | 3.2 ± 0.5 | 1.9 ± 1.0 | 0.005 |
| Plasma insulin (ng·ml−1) | 0.34 ± 0.15 | 0.14 ± 0.07 | 0.0008 |
| Plasma IGF-1 (ng·ml−1) | 114.8 ± 38.5 | 43.6 ± 34.1 | <0.0001 |
Values are means ± SD. P-values from Student’s t-tests or Mann Whitney tests are shown.
†
indicates n=8,
Δ
indicates n=11