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. 2022 Apr 12;11:e70779. doi: 10.7554/eLife.70779

Table 6. The enrichment of drug-gene interaction terms in DGIdb for the susceptibility genes identified by MAGMA, S-PrediXcan and eDESE.

Table 6—source data 1. The drug-gene interaction term results of the potential susceptibility genes of schizophrenia identified by MAGMA in DGIdb.
Table 6—source data 2. The drug-gene interaction term results of the potential susceptibility genes of schizophrenia identified by S-PrediXcan in DGIdb.
Table 6—source data 3. The drug-gene interaction term results of the potential susceptibility genes of schizophrenia identified by eDESE:dist in DGIdb.
Table 6—source data 4. The drug-gene interaction term results of the potential susceptibility genes of schizophrenia identified by eDESE:gene in DGIdb.
Table 6—source data 5. The drug-gene interaction term results of the potential susceptibility genes of schizophrenia identified by eDESE:isoform in DGIdb.
Models # of antipsychotics-gene interaction terms # of total drug-gene interaction terms Enrichment p*
MAGMA 57 937 1.62e-11
S-PrediXcan 12 452 0.33
eDESE:dist 34 279 1.56e-15
eDESE:gene 56 968 1.65e-10
eDESE:isoform 70 1,104 8.74e-15
*

Enrichment p denotes the p-value of the hypergeometric distribution test. See also Table 6—source data 1, Table 6—source data 2, Table 6—source data 3, Table 6—source data 4, and Table 6—source data 5.