TABLE 2.
Susceptibility of constructed mutants and their parent strains to antimicrobial agents
| Strain | Genotypea
|
MIC (μg/ml) ofb:
|
||||||
|---|---|---|---|---|---|---|---|---|
| AB | XY | M | OFX | TEC | ERY | GEN | STR | |
| PAO1 | + | + | + | 0.5 | 16 | 256 | 1 | 16 |
| N101 | + | − | + | 0.25 | 2 | 64 | 0.13 | 2 |
| KG2225 | − | + | + | 0.13 | 2 | 64 | 1 | 4,096 |
| N102 | − | − | + | 0.03 | 0.5 | 32 | 0.13 | 512 |
| KG2239 | − | + | − | 0.03 | 0.5 | 16 | 0.25 | 2 |
| N103 | − | − | − | 0.03 | 0.25 | 16 | 0.25 | 2 |
| KG2239/pAK1900 | − | + | − | 0.03 | 0.25 | 16 | 0.13 | 2 |
| KG2239/pKMM128 | − | + | + | 0.13 | 8 | 64 | 1 | 16 |
| N103/pAK1900 | − | − | − | 0.03 | 0.13 | 16 | 0.13 | 2 |
| N103/pKMM128 | − | − | + | 0.03 | 0.13 | 16 | 0.13 | 2 |
| N126 | − | + | + | 0.13 | 16 | 128 | 1 | 8 |
| N128 | − | − | + | 0.03 | 0.5 | 32 | 0.13 | 1 |
a
AB, mexAB possessing (+) or -deficient (−); XY, mexXY possessing (+) or deficient (−); M, oprM (+) or deficient (−).
b
Abbreviations: OFX, ofloxacin; TEC, tetracycline; ERY, erythromycin; GEN, gentamicin; STR, streptomycin.