Table 3.
The Association Between Hospital Length of Stay (LOS) and Immunological Responses & Pulmonary Lesions in TB Patients with or without DM
| TB-NDM (n = 159) | Total | TB-DM (n = 168) | Total | |||
|---|---|---|---|---|---|---|
| LOS ≤ 2 Weeks (n = 100) | LOS> 2 Weeks (n = 59) | LOS ≤ 2 Weeks (n = 111) | LOS> 2 Weeks (n = 57) | |||
| IGRA-ELISPOT | ||||||
| Positive (%) | 47 (47.0%) | 17 (28.8%) | 64 | 49 (44.1%) | 27 (47.4%) | 76 |
| Negative (%) | 18 (18.0%) | 15 (25.4%) | 37 | 30 (27.0%) | 11 (19.3%) | 41 |
| IGRA-ELISA | ||||||
| Positive (%) | 19 (19.0%) | 12 (20.3%) | 37 | 16 (14.4%) | 11 (19.3%) | 27 |
| Negative (%) | 16 (16.0%) | 15 (25.4%) | 31 | 16 (14.4%) | 8 (14.0%) | 24 |
| 38kD+16kD | ||||||
| Positive (%) | 28 (28.0%) | 15 (25.4%) | 43 | 33 (29.7%) | 18 (31.6%) | 51 |
| Negative (%) | 72 (72.0%) | 44 (74.6%) | 116 | 78 (70.3%) | 39 (68.4%) | 117 |
| Pulmonary lobe lesion | ||||||
| Mild (1–2 lobes) (%) | 69 (69.0%) | 28 (47.5%)α (P=0.0112) 2.464 [1.250, 4.699]※※ |
97 | 62 (55.9%) | 24 (42.1%) | 86 |
| Severe (3–5 lobes) (%) | 31 (31.0%) | 31 (52.5%) | 62 | 49 (44.1%) | 33 (57.9%) | 82 |
| Pulmonary cavity | ||||||
| NO (%) | 85 (85.0%) | 47 (79.7%) | 132 | 81 (73.0%)β (P=0.0430) 2.099 [1.038, 4.151]※※ |
37 (64.9%) | 118γ (P=0.0089) 5.038 [2.976, 8.415]※ |
| Yes (%) | 15 (15.0%) | 12 (20.3%) | 27 | 30 (27.0%) | 20 (35.1%) | 50 |
Notes: Results between each two groups were compared using the Chi-square test or Fisher’s exact test according to the sample size. P-value < 0.05 was considered as a significant difference and was showed in bold text. αP value from LOS>2 weeks TB-NDM group vs LOS ≤2 weeks TB-NDM group. βP value from LOS ≤2 weeks TB-DM group vs LOS ≤2 weeks TB-NDM group. γP value from TB-NDM group vs TB-DM group. ※※The odds ratios (ORs) and their 95% confidence interval (CI) were calculated by Baptista–Pike method.
Abbreviation: LOS, hospital length of stay.