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. 2022 Apr 12;13:1970. doi: 10.1038/s41467-022-29539-3

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© The Author(s) 2022, corrected publication 2024

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Fig. 6 — a Kaplan–Meier curves showing the proportion of patients whose steroid monotherapy failed and warranted disease-modifying anti-rheumatic drugs (DMARDs) over 12 months of follow-up based on ICI regimen. Two-sided Log rank test. P, PD-1 inhibitor arthritis; C, Combined ICI arthritis. b Percentage of interferon gamma (IFNγ)- and interleukin (IL)-17–producing CD4⁺ T cells in PB (left panels) and Th1, transient (t-)Th17, and Th17 cells (right panels) before and after treatment of arthritis from 7 patients with arthritis-irAE. One-sided Wilcoxon matched-pairs signed-rank test. c Percentage of IFNγ- and IL-17–producing CD8⁺ T cells in PB (left panels) and Tc1, t-Tc17, and Tc17 cells (right panels) before and after treatment of arthritis from 7 patients with arthritis-irAE. One-sided Wilcoxon matched-pairs signed-rank test. d Concentration of inflammatory cytokines in serum before and after treatment of arthritis from 7 patients with arthritis-irAE. One-sided Wilcoxon matched-pairs signed-rank test. Source data are provided as a Source Data file.