Western blots of protein lysates from porcine ischemic myocardial tissue were performed as indicated with quantitative analyses normalized to α-tubulin and representative images (A) TNFα, (B) NOX2, (C) NOX4, (D) catalase, (E) SOD1, (F) SOD2. Blots for (A), (B), and (C) are provided in supplementary Figure S1. Data is graphed as mean with SEM, with main effect of diet as large bracket and main effect of EVs as inner brackets. TNFα, tumor necrosis factor α; NOX2/4, NADPH oxidase 2/4; SOD1/2, superoxide dismutase 1/2.