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. 2022 Apr 12;13:1955. doi: 10.1038/s41467-022-29580-2

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Overall structure of the subcomplex. Cartoon representations of the TED domain and part of the CUB^g segment are colored in splitpea and the αI domain of CR3 in gold. The Mg²⁺ cation of the MIDAS motif is shown as a green sphere. b Zoom into the Mg²⁺ coordination sphere. Distances between oxygen atoms and the Mg²⁺ ion are shown as wheat dashed lines. c, d Two side views into the TED-αI interface related by an almost 180° rotation around a vertical axis. In addition to the coordination bonds, interchain hydrogen bonds are shown as dashed lines (colored in yellow).