Table 1.
Clinical characteristics of the study population (n = 217).
| Mean ±SD or n (%) | P-value | |||||
|---|---|---|---|---|---|---|
|
All patients (n = 217) |
Co-existing hypertension and H-Hcy (n = 82) |
Isolated hypertension (n = 69) |
Isolated H-Hcy (n = 30) |
Control group (n = 36) |
||
| Age, years | 59.4 ± 11.9 | 61.2 ± 10.6 | 60.4 ± 10.4 | 57.8 ± 12.1 | 54.8 ± 15.6 | 0.039 |
| Gender, male | 154 (71.0) | 65 (79.3) | 39 (56.5) | 25 (75.8) | 25 (75.8) | 0.007 |
| BMI, kg/m2 | 25.3 ± 3.5 | 25.5 ± 3.5 | 26.0 ± 3.0 | 23.9 ± 3.7 | 24.8 ± 3.4 | 0.053 |
| History of hyperlipidemia | 100 (46.1) | 44 (53.7) | 28 (40.5) | 16 (42.4) | 12 (42.4) | 0.042 |
| HDL, mmol/l | 1.1 ± 0.4 | 1.1 ± 0.4 | 1.2 ± 0.6 | 1.05 ± 0.2 | 1.02 ± 0.2 | 0.038 |
| LDL, mmol/l | 2.8 ± 1.2 | 2.9 ± 1.2 | 2.9 ± 1.4 | 2.9 ± 0.8 | 2.3 ± 0.9 | 0.055 |
| TG, mmol/l | 1.6 ± 0.9 | 1.7 ± 0.9 | 1.6 ± 0.8 | 1.5 ± 1.1 | 1.4 ± 0.8 | 0.480 |
| TC, mmol/l | 4.4 ± 1.2 | 4.5 ± 1.2 | 4.5 ± 1.2 | 4.5 ± 1.0 | 3.9 ± 1.0 | 0.058 |
| Hcy, μmol/L | 17.9 ± 11.0 | 23.2 ± 9.2 | 11.3 ± 2.1 | 26.4 ± 13.9 | 10.0 ± 3.3 | <0.001 |
| Stain use | 104 (47.9) | 45 (54.9) | 28 (40.6) | 16 (47.0) | 15 (47.0) | 0.096 |
| Antihypertension treatment | 114 (52.5) | 57 (69.5) | 50 (72.5) | 0 (0) | 0 (0) | 0.001 |
| History of smoking | 128 (59.0) | 58 (70.7) | 32 (46.4) | 22 (57.6) | 16 (57.6) | 0.002 |
| History of diabetes | 68 (31.3) | 21 (25.6) | 31 (44.9) | 7 (24.2) | 9 (24.2) | 0.035 |
| History of CHD | 27 (12.4) | 13 (15.9) | 9 (13.4) | 1 (7.6) | 4 (7.6) | 0.260 |
BMI, body mass index; HDL, high-density lipoprotein; LDL, low-density lipoprotein; TG, Triglycerides; TC, Total cholesterol; Hcy, homocysteine; CHD, coronary heart disease.