Table 4.
Cox regression hazard models of risk factors for vascular events.
| Vascular events | ||||||
|---|---|---|---|---|---|---|
| Univariate regression | Multivariate regression* | |||||
| HR | 95% CI | P-value | HR | 95% CI | P-value | |
| Hypertension | 2.16 | 1.14–1.09 | 0.018* | 1.00 | 0.38–2.64 | 0.966 |
| H-Hcy | 1.09 | 0.88–1.35 | 0.442 | 1.58 | 0.84–2.97 | 0.159 |
| Presence of carotid LRNC | 2.28 | 1.27–4.09 | 0.006* | 2.25 | 1.09–4.65 | 0.029* |
| Co-existing hypertension and H-Hcy | 1.97 | 1.19–3.27 | 0.009* | 1.82 | 1.01–3.27 | 0.044* |
| Combination of co-existing hypertension and H-Hcy and carotid LRNC | 2.44 | 1.46–4.06 | 0.001* | 2.39 | 1.26–4.43 | 0.007* |
*
Confounding factors: age, gender, BMI, antihypertension treatment, history of hyperlipidemia and diabetes, and carotid calcification. LRNC, lipid-rich necrotic core; HR, hazard ratio.