Figure 1.

Representation of the complete arterial topology (used in the computer model with the hand and foot topologies, adapted from Reymond et al., 2009). (i) Control with two kidneys configuration (2KDN), kidneys in their usual anatomical location on the aorta. (ii) One kidney configuration (1KDN), the left renal artery (segment 36) is disconnected from the model. (iii) Zero kidneys configuration (0KDN), simulated by removing both the right and the left renal arteries, segments 36 and 38. (iv) Transplanted configuration (TX), both renal arteries were disconnected, the right renal artery (segment 38) was attached into the external iliac artery (segment 44).