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. 2022 Apr 12;12(4):e820. doi: 10.1002/ctm2.820

FIGURE 1.

FIGURE 1

Regulation of SLC7A11. The finding by Liu et al. is highlighted in box. (1) Upregulation of METTL3 in HB leads to an increased level of m6A modification on SLC7A11. (2) Recognition of m6A‐modified SLC7A11 by IGF2BP1. (3) As a result, SLC7A11 is stabilized as DA complex is no longer able to interact with SLC7A11. DA complex, deadenylation complex involved in degradation of mRNA