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. 2022 Mar 30;13:825413. doi: 10.3389/fmicb.2022.825413

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Copyright © 2022 Pan, Huang, Jia, Deng, Chen, Wei, Zhang, Li, Sun, Fang, Ren, Xing, Chen, Li, Du, Chen, Gao and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Flow chart of the study participants. Of the 1,307 patients with suspected TB and 172 healthy controls recruited, 352 definite TB patients and 153 healthy controls with lower risk of Mycobacterium tuberculosis (M.tb) infection were eligible for inclusion in the final analysis. TB, tuberculosis; CT, computed tomography; AFB, acid-fast bacilli; TBLB, transbronchial lung biopsy.