Fig. 4.

Gross evaluation of the osteochondral repair by mosaicplasty surgery in a rabbit model. (A) Schematic diagram of the surgical procedure of the mosaic transplantation. Autologous osteochondral graft transplantation mimicking mosaicplasty is shown; the remaining gap was filled with GelMA hydrogel with or without IGF-1bsn, and any type of gel was not used to fill the gap in the blank group. (B) Gross view of the samples harvested 6 weeks post transplantation. (C) Gross view of the samples harvested 12 weeks post transplantation. (D) Analysis of ICRS score for the harvested samples. n = 6 per group; ns: not significant; *p < 0.05, **p < 0.01, ****p < 0.0001.